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SKICEF 1.5GM (CEFUROXIME IN)

SKICEF 1.5GM (CEFUROXIME IN)

Key Uses

  • Pre-operative surgical prophylaxis to reduce the incidence of post-surgical site infections
  • Treatment of severe lower respiratory tract infections, including bacterial pneumonia
  • Management of complicated urinary tract infections, pyelonephritis, and skin structure infections
  • Treatment of systemic bacterial septicemia, bone and joint infections, and acute gonococcal urethritis

How It Works
Cefuroxime is a bactericidal agent that acts by disrupting bacterial cell wall synthesis. It binds selectively to specific penicillin-binding proteins located inside the bacterial cell wall, which inhibits the final transpeptidation step of peptidoglycan synthesis. This structural interruption weakens the cell wall, leading to bacterial cell wall instability, osmotic lysis, and subsequent death of the active bacterial organism.Directions for Use

  • Administer via deep intramuscular injection, slow direct intravenous injection, or continuous intravenous infusion
  • Reconstitute the sterile powder using the provided sterile water for injection according to standard hospital protocols
  • Shake vigorously until the powder dissolves completely and inspect visually for particles or discoloration before drawing
  • Must be prepared, calculated, and administered exclusively by a registered doctor, nurse, or healthcare professional

Key Features

  • High-potency broad-spectrum antibiotic with strong resistance against degradation by bacterial beta-lactamase enzymes
  • Dual action formulation suitable for both immediate therapeutic treatment and pre-surgical infection prevention
  • Packaged in a high-grade sterile glass vial alongside a dedicated ampoule of sterile water for accurate reconstitution
  • Manufactured under stringent current Good Manufacturing Practices standards by Neon Laboratories Ltd

Important Safety Notes

  • Storage Temperature: Store below 25°C in a cool, dry place. Protect from direct light lines and do not freeze. Use the reconstituted solution immediately or within specified clinical timing rules.
  • Contraindicated in individuals with a documented history of severe hypersensitivity or anaphylactic reactions to cephalosporins or penicillins
  • Use with advanced clinical caution in patients with pre-existing renal impairment or a history of gastrointestinal disease like colitis

SKICEF 1.5GM – Cefuroxime Sodium For Injection I.P.
Brand: SKICEF Injection
Content: Sterile Cefuroxime Sodium I.P. equivalent to Cefuroxime 1.5 g (1500 mg)
Company / Manufacturer: Neon Laboratories Ltd
Pack: Vial with Sterile Water for Injection
Category: Second-Generation Cephalosporin AntibioticProduct Description
SKICEF 1.5gm is a sterile, second-generation cephalosporin antibiotic powder formulated for parenteral administration. It exhibits broad-spectrum bactericidal activity against a wide range of clinically significant Gram-positive and Gram-negative micro-organisms. It is extensively utilized in clinical settings, emergency wards, and surgical suites to treat serious systemic bacterial infections and to provide effective surgical prophylaxis to prevent post-operative wound infections.

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