NEOROF 20ML VIAL – Propofol Injectable Emulsion I.P.
Brand: NEOROF Injection
Content: Propofol Injectable Emulsion I.P. 1% w/v
Company / Manufacturer: Neon Laboratories Ltd
Pack: 20 ml Vial
Category: General Anesthetic / Sedative-Hypnotic AgentProduct Description
NEOROF 20ml Vial contains Propofol, a short-acting intravenous general anesthetic formulated as a sterile lipid emulsion. It is used in operating theaters and intensive care units to induce and maintain general anesthesia or provide continuous sedation for critically ill patients. The oil-in-water emulsion formulation allows the active lipophilic compound to dissolve efficiently, providing an ultra-rapid onset of action and a smooth recovery profile.Key Uses
- Induction of general anesthesia in patients undergoing surgical operations
- Maintenance of general anesthesia throughout the duration of prolonged surgeries
- Continuous sedation for critically ill adult patients undergoing mechanical ventilation in the ICU
- Monitored anesthesia care for diagnostic, procedural, or minor surgical interventions
How It Works
Propofol acts as a positive allosteric modulator of the Gamma-Aminobutyric Acid type A receptor complex in the central nervous system. By binding to these specific receptors, it enhances the inhibitory actions of GABA, increasing chloride ion conduction across nerve cells. This mechanism depresses central nervous activity, producing a rapid and controlled loss of consciousness.Directions for Use
- Administer strictly via intravenous injection or continuous intravenous infusion routes
- Shake the vial thoroughly before use to ensure the lipid emulsion layer is uniform
- Visually inspect for any phase separation or discoloration before drawing
- Must be administered exclusively by a registered anesthesiologist or clinician
Key Features
- Ultra-rapid therapeutic action that induces deep sedation within forty seconds
- Clear and highly predictable recovery profile allowing patients to awaken quickly
- Formulated in a stable soybean oil based emulsion vehicle for uniform drug delivery
- Manufactured under stringent sterile conditions to prevent contamination by Neon Laboratories Ltd
Possible Side Effects
- Transient pain or burning sensations localized at the injection site
- Hypotension or sudden temporary drop in systemic blood pressure
- Bradycardia, slow heart rate, or mild changes in breathing patterns









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